Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14799870 | 1.00 | MEN1 (0.35) | MEN1KMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL14799204 | 0.95 | GAA (0.36) | MEN1KMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL14799203 | 0.95 | GAA (0.36) | MEN1KMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL14800049 | 0.90 | MEN1 (0.38) | MEN1KMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL15439445 | 0.89 | HIF1A (0.35) | MEN1KMT2AMAPK1L3MBTL1NPC1 | |
| SCHEMBL15439444 | 0.89 | HIF1A (0.35) | MEN1KMT2AMAPK1L3MBTL1NPC1 | |
| SCHEMBL15762585 | 0.87 | GAA (0.36) | MEN1KMT2AMAPK1L3MBTL1GAA | |
| SCHEMBL15440292 | 0.85 | HIF1A (0.40) | MEN1KMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL15440290 | 0.85 | HIF1A (0.40) | MEN1KMT2AMAPK1L3MBTL1POLB | |
| SCHEMBL15763282 | 0.82 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |