Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440290 | 1.00 | HIF1A (0.40) | HIF1AGAAMEN1KMT2APOLB | |
| SCHEMBL15439444 | 0.96 | HIF1A (0.35) | HIF1AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL15439445 | 0.96 | HIF1A (0.35) | HIF1AMEN1KMT2ANPC1MAPK1 | |
| SCHEMBL14799204 | 0.89 | GAA (0.36) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL14799203 | 0.89 | GAA (0.36) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL15440364 | 0.88 | MEN1 (0.32) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL15440365 | 0.88 | MEN1 (0.32) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL14799871 | 0.85 | MEN1 (0.35) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL14799870 | 0.85 | MEN1 (0.35) | GAAMEN1KMT2APOLBCASP6 | |
| SCHEMBL14800050 | 0.80 | MEN1 (0.38) | GAAMEN1KMT2APOLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |