Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492409 | 1.00 | G6PC1 (0.42) | G6PC1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15440103 | 0.93 | NPC1 (0.40) | G6PC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL15440106 | 0.93 | NPC1 (0.40) | G6PC1NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL14800291 | 0.92 | G6PC1 (0.40) | G6PC1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL14800293 | 0.92 | G6PC1 (0.40) | G6PC1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL14799590 | 0.92 | G6PC1 (0.46) | G6PC1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL14799593 | 0.92 | G6PC1 (0.46) | G6PC1NPC1RAB9AALDH1A1TSHR | |
| SCHEMBL15439707 | 0.86 | NPC1 (0.44) | G6PC1NPC1RAB9AALDH1A1GAA | |
| SCHEMBL15439709 | 0.86 | NPC1 (0.44) | G6PC1NPC1RAB9AALDH1A1GAA | |
| SCHEMBL14799642 | 0.85 | G6PC1 (0.46) | G6PC1NPC1RAB9AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | claimed |
| US-8962766-B2 | Polymers functionalized with polyhydrazone compounds | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130079463-A1 | POLYMERS FUNCTIONALIZED WITH POLYHYDRAZONE COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2013-03-28 | — | — | US | disclosed |