SCHEMBL14799983

SCHEMBL14799983

CC1(C)OCCN2CCOCCOCCN(CCOC1(C)C)CCOC(C)(C)C(C)(C)OCC2

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MGLL Q99685 1/20 0.31
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18879746 0.83 SMN1; SMN2 (0.38) SMN1; SMN2GAAALDH1A1
SCHEMBL17465535 0.80 SMN1; SMN2 (0.50) SMN1; SMN2GAAALDH1A1
SCHEMBL18879744 0.79
SCHEMBL9735039 0.78 TTR (0.43) SMN1; SMN2TTR
SCHEMBL5317147 0.78 TTR (0.43) SMN1; SMN2TTR
SCHEMBL11552627 0.78 TTR (0.50) SMN1; SMN2ALDH1A1MGLLTTR
SCHEMBL27017 0.78 TTR (0.50) SMN1; SMN2ALDH1A1MGLLTTR
SCHEMBL31229527 0.78 TTR (0.50) SMN1; SMN2ALDH1A1MGLLTTR
SCHEMBL11554965 0.78 TTR (0.50) SMN1; SMN2ALDH1A1MGLLTTR
SCHEMBL25928 0.78 TTR (0.50) SMN1; SMN2ALDH1A1MGLLTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9655982-B2 Formation and uses of europium complexes WAYNE STATE UNIVERSITY (US) 2017-05-23 US disclosed
US-9655982-B2 Formation and uses of europium complexes WAYNE STATE UNIVERSITY (US) 2017-05-23 US disclosed
US-20130078189-A1 FORMATION AND USES OF EUROPIUM COMPLEXES Wayne State Univeristy 2013-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130078189-A1 FORMATION AND USES OF EUROPIUM COMPLEXES SELE, EFTUD2, SLC7A5 SMN1; SMN2 2039/4885GAA 2922/4885ALDH1A1 4568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.