SCHEMBL14801792

SCHEMBL14801792

Nc1c(C(=O)O)cc(O)cc1C(=O)/C=C/c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.62
GUSB P08236 1/20 0.61
MEN1 O00255 2/20 0.57
CYP3A4 P08684 2/20 0.57
KMT2A Q03164 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ALDH1A1 P00352 1/20 0.57
THRB P10828 1/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
MAPK1 P28482 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HSD17B10 Q99714 1/20 0.57
SLC5A1 P13866 1/20 0.56
SLC5A2 P31639 1/20 0.56
BCHE P06276 1/20 0.55
CYP2C19 P33261 1/20 0.55
AR P10275 1/20 0.55
NPC1 O15118 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14801794 1.00 MAPT (0.62) MAPTGUSBMEN1CYP3A4KMT2A
SCHEMBL14802035 0.85 KMT2A (0.61) MAPTMEN1CYP3A4KMT2ATDP1
SCHEMBL14802092 0.84 CHRNA7 (0.63) MAPTGUSBMAPK1BCHEAR
SCHEMBL14802094 0.84 CHRNA7 (0.63) MAPTGUSBMAPK1BCHEAR
SCHEMBL2843086 0.83 MAPT (0.73) MAPTGUSBMEN1CYP3A4KMT2A
SCHEMBL2843080 0.83 MAPT (0.73) MAPTGUSBMEN1CYP3A4KMT2A
SCHEMBL27821482 0.80 MAPT (0.72) MAPTGUSBMEN1CYP3A4KMT2A
SCHEMBL14802091 0.80 MAPT (0.64) MAPTGUSBMEN1CYP3A4KMT2A
SCHEMBL15664702 0.80 GUSB (0.72) MAPTGUSBMEN1CYP3A4KMT2A
SCHEMBL14801788 0.79 CHRNA7 (0.71) MAPTMEN1CYP3A4KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed