SCHEMBL14802091

SCHEMBL14802091

Nc1c(C(=O)O)ccc(C(=O)C=Cc2ccccc2)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.64
CYP1B1 Q16678 8/20 0.60
ABCG2 Q9UNQ0 2/20 0.60
CYP1A1 P04798 3/20 0.58
BCHE P06276 2/20 0.57
CYP2C19 P33261 1/20 0.57
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TDP1 Q9NUW8 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
THRB P10828 2/20 0.55
HPGD P15428 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
CYP3A4 P08684 2/20 0.55
ALOX15 P16050 1/20 0.55
MAPK1 P28482 1/20 0.55
HSD17B10 Q99714 1/20 0.55
GUSB P08236 1/20 0.51
LMNA P02545 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2843080 0.84 MAPT (0.73) MAPTCYP1B1ABCG2CYP1A1BCHE
SCHEMBL2843086 0.84 MAPT (0.73) MAPTCYP1B1ABCG2CYP1A1BCHE
SCHEMBL14801709 0.82 TERT (0.69) MAPTMEN1KMT2ATDP1KDM4E
SCHEMBL28859257 0.82 ABCG2 (0.57) MAPTCYP1B1ABCG2CYP1A1BCHE
SCHEMBL14801792 0.80 MAPT (0.62) MAPTCYP1B1ABCG2CYP1A1BCHE
SCHEMBL14801794 0.80 MAPT (0.62) MAPTCYP1B1ABCG2CYP1A1BCHE
SCHEMBL131599 0.79 TERT (0.69) MAPTCYP1B1ABCG2BCHECYP2C19
SCHEMBL634100 0.79 TERT (0.69) MAPTCYP1B1ABCG2BCHECYP2C19
SCHEMBL27579527 0.79 MAPT (0.77) MAPTCYP1B1ABCG2BCHECYP2C19
SCHEMBL1501349 0.78 MAPT (1.00) MAPTCYP1B1ABCG2CYP1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280441-B2 Host cells and methods for producing cinnamoyl anthranilate and analogs thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2019-05-07 US disclosed
US-20130078683-A1 Host Cells and Methods for Producing Cinnamoyl Anthranilate and Analogs Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-03-28 US disclosed