Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 12/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14447683 | 0.92 | PRKDC (0.46) | PRKDCP2RY12XDH | |
| SCHEMBL14468620 | 0.90 | PRKDC (0.47) | PRKDCP2RY12XDH | |
| SCHEMBL14802156 | 0.88 | PRKDC (0.59) | PRKDCP2RY12XDH | |
| SCHEMBL5446334 | 0.87 | PRKDC (0.51) | PRKDCP2RY12XDH | |
| SCHEMBL14802151 | 0.86 | PRKDC (0.46) | PRKDCP2RY12XDH | |
| SCHEMBL5441507 | 0.85 | PRKDC (0.47) | PRKDCP2RY12XDH | |
| SCHEMBL14802150 | 0.84 | PRKDC (0.48) | PRKDC | |
| SCHEMBL14802144 | 0.83 | ALDH1A1 (0.47) | PRKDCP2RY12 | |
| SCHEMBL5444190 | 0.83 | PRKDC (0.56) | PRKDC | |
| SCHEMBL14468611 | 0.82 | PRKDC (0.43) | PRKDCXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404681-B2 | Xanthones, thioxanthones and acridinones as DNA-PK inhibitors | LUITPOLD PHARMACEUTICALS, INC. (US) | 2013-03-26 | — | — | US | disclosed |