Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802509 | 0.99 | MEN1 (0.38) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL14802630 | 0.98 | PRSS1 (0.39) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL14802473 | 0.95 | POLB (0.34) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL14802570 | 0.92 | POLB (0.33) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL13611326 | 0.89 | PRSS1 (0.45) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL13611329 | 0.88 | PRSS1 (0.44) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL14802576 | 0.87 | MAPK1 (0.37) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL11956787 | 0.87 | PRSS1 (0.34) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL16573656 | 0.86 | SERPINE1 (0.35) | MEN1KMT2APRSS1PRSS2PRSS3 | |
| SCHEMBL13611354 | 0.86 | PRSS1 (0.47) | PRSS1PRSS2PRSS3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160250374-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ORTHOCON, INC. | 2016-09-01 | — | — | US | disclosed |
| US-9314547-B2 | Absorbable multi-putty bone cements and hemostatic compositions and methods of use | ABYRX INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20130078300-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2013-03-28 | — | — | US | disclosed |