Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611329 | 0.99 | PRSS1 (0.44) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL13611354 | 0.97 | PRSS1 (0.47) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL13611320 | 0.94 | TSHR (0.41) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL13624646 | 0.91 | TDP1 (0.44) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL13611328 | 0.90 | SERPINE1 (0.40) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL14802444 | 0.89 | MEN1 (0.38) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL14802509 | 0.88 | MEN1 (0.38) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL14802630 | 0.86 | PRSS1 (0.39) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL9751347 | 0.86 | TDP1 (0.55) | PRSS1PRSS2PRSS3TDP1TSHR | |
| SCHEMBL13624643 | 0.85 | TDP1 (0.46) | TDP1TSHRCYP1A2CYP2D6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11116866-B2 | Multi-putty adhesive and cement compositions for tissue hemostasis, repair and reconstruction | ABYRX, INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-20200061236-A1 | MULTI-PUTTY ADHESIVE AND CEMENT COMPOSITIONS FOR TISSUE HEMOSTASIS, REPAIR AND RECONSTRUCTION | ORTHOCON, INC. | 2020-02-27 | — | — | US | disclosed |
| US-20190099514-A1 | MULTI-PUTTY ADHESIVE AND CEMENT COMPOSITIONS FOR TISSUE HEMOSTASIS, REPAIR AND RECONSTRUCTION | ORTHOCON, INC. | 2019-04-04 | — | — | US | disclosed |
| US-20160250374-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ORTHOCON, INC. | 2016-09-01 | — | — | US | disclosed |
| US-9314547-B2 | Absorbable multi-putty bone cements and hemostatic compositions and methods of use | ABYRX INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-20130078300-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, LLC (US) | 2013-03-28 | — | — | US | disclosed |
| US-8367747-B2 | Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367747-B2 | Bioabsorbable polymers from bioabsorbable polyisocyanates and uses thereof | BEZWADA BIOMEDICAL, LLC (US) | 2013-02-05 | — | — | US | disclosed |
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, L.L.C (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | BEZWADA BIOMEDICAL, L.L.C (US) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090292029-A1 | BIOABSORBABLE POLYMERS FROM BIOABSORBABLE POLYISOCYANATES AND USES THEREOF | PUF60, PFAS, UROD | PRSS1 75/4885PRSS2 163/4885PRSS3 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.