Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24237029 | 1.00 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24523105 | 1.00 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL14329533 | 0.99 | KCNA3 (0.74) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24522923 | 0.89 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24522756 | 0.89 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24522855 | 0.86 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL9188366 | 0.86 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24523082 | 0.86 | KCNA3 (0.72) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24237031 | 0.86 | KCNA3 (0.97) | KCNA3CA12CA1CA9MAOB | |
| SCHEMBL24522731 | 0.84 | KCNA3 (0.67) | KCNA3CA12CA1CA9MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859776-B2 | Substituted piperidines that increase p53 activity and the uses thereof | MERCK SHARP & DOHME CORP. (US) | 2014-10-14 | — | — | US | disclosed |
| US-20130079394-A1 | Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods | CNRS (CENTRE NATIONAL RECHERCHE SCIENTIFIQUE) (FR) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079394-A1 | Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods | NISCH, ACAT2, CIAPIN1 | KCNA3 1483/4885CA12 3214/4885CA1 2751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.