Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926994 | 0.89 | ANO1 (0.67) | ANO1ANO2 | |
| SCHEMBL29059603 | 0.89 | ANO1 (1.00) | ANO1ANO2 | |
| SCHEMBL14818567 | 0.88 | ANO1 (0.74) | ANO1ANO2 | |
| SCHEMBL12271278 | 0.85 | ANO1 (0.80) | ANO1ANO2 | |
| SCHEMBL3631114 | 0.84 | ANO1 (0.83) | ANO1ANO2 | |
| SCHEMBL14803221 | 0.84 | ANO1 (0.63) | ANO1ANO2 | |
| SCHEMBL6926996 | 0.83 | ANO1 (0.73) | ANO1ANO2 | |
| SCHEMBL6928204 | 0.83 | ANO1 (0.71) | ANO1ANO2 | |
| SCHEMBL13926174 | 0.83 | ANO1 (0.72) | ANO1ANO2 | |
| SCHEMBL6925595 | 0.83 | ANO1 (0.77) | ANO1ANO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | ANO1 114/4885ANO2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.