Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953247 | 0.87 | ANO1 (1.00) | ANO1ANO2 | |
| SCHEMBL14803236 | 0.83 | ANO1 (0.80) | ANO1ANO2 | |
| SCHEMBL14803206 | 0.82 | ANO1 (0.66) | ANO1ANO2 | |
| SCHEMBL3631114 | 0.82 | ANO1 (0.83) | ANO1ANO2 | |
| SCHEMBL6928204 | 0.81 | ANO1 (0.71) | ANO1ANO2 | |
| SCHEMBL6926443 | 0.80 | ANO1 (0.60) | ANO1ANO2 | |
| SCHEMBL12271278 | 0.80 | ANO1 (0.80) | ANO1ANO2 | |
| SCHEMBL1952997 | 0.80 | ANO1 (0.71) | ANO1ANO2 | |
| SCHEMBL28599811 | 0.80 | MEN1 (0.79) | ANO1ANO2 | |
| SCHEMBL14818485 | 0.79 | ANO1 (0.65) | ANO1ANO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| WO-2011109551-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2011-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | ANO1 114/4885ANO2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.