Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ANO1 | Q5XXA6 | 6/20 | 0.45 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14803124 | 0.93 | MEN1 (0.47) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14803348 | 0.92 | MEN1 (0.46) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14803139 | 0.89 | MAPT (0.51) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL1954046 | 0.89 | LMNA (0.49) | RAB9ANPC1MEN1KMT2ANLRP3 | |
| SCHEMBL14803515 | 0.88 | MEN1 (0.51) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14803292 | 0.87 | MEN1 (0.47) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14818448 | 0.84 | ANO1 (0.56) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14803519 | 0.84 | ANO1 (0.46) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14803193 | 0.83 | GRIN2C (0.43) | RAB9ANPC1MEN1KMT2AANO1 | |
| SCHEMBL14803195 | 0.83 | MEN1 (0.49) | RAB9ANPC1MEN1KMT2AANO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA, INC. (US) | 2013-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079348-A1 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | ORAI1, SARAF, RYR2 | RAB9A 1174/4885NPC1 262/4885MEN1 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.