⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15932163 | 1.00 | — | — | |
| SCHEMBL6901523 | 1.00 | — | — | |
| SCHEMBL3281141 | 1.00 | — | — | |
| SCHEMBL6023550 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL31255671 | 0.76 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL28564370 | 0.76 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL28783865 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL30084769 | 0.76 | KDM4E (0.33) | — | |
| SCHEMBL13017487 | 0.75 | — | — | |
| SCHEMBL26940437 | 0.73 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20240025898-A1 | HPK1 ANTAGONISTS AND USES THEREOF | SCHRÖDINGER, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20230374035-A1 | RAS INHIBITORS | Revolution Medicines, Inc. | 2023-11-23 | — | — | US | disclosed |
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-11767341-B2 | Lincosamide antibiotics and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-09-26 | — | — | US | disclosed |
| US-20230233569-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT | 2023-07-27 | — | — | US | disclosed |
| US-11692131-B2 | Heteroleptic transition metal-carbene complexes and their use in organic light-emitting diodes | UDC IRELAND LIMITED (IE) | 2023-07-04 | — | — | US | disclosed |
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-11542255-B2 | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors | INFLAZOME LIMITED (IE) | 2023-01-03 | — | — | US | disclosed |
| US-11535576-B2 | Carbonyl containing compound high-throughput quantitative analysis using isobaric multiplex reagents | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-12-27 | — | — | US | disclosed |
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100240924-A1 | 2-ETHYL-4,6-DIMETHYL-PHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PEST CONTROL AGENTS AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-23 | — | — | US | disclosed |
| US-20100190770-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2010-07-29 | — | — | US | disclosed |
| US-20100093819-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20090096367-A1 | HETEROLEPTIC TRANSITION METAL-CARBENE COMPLEXES AND THEIR USE IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF SE (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20090054657-A1 | Transition Metal Complexes Comprising One Noncarbene Ligand and One or Two Carbene Ligands and their Use in Oleds | BASF SE (DE) | 2009-02-26 | — | — | US | disclosed |
| US-20090018330-A1 | PROCESS FOR PREPARING TRANSITION METAL-CARBENE COMPLEXES | BASF SE (DE) | 2009-01-15 | — | — | US | disclosed |
| US-20070282076-A1 | Transition Metal Carbene Complexes Embedded in Polymer Matrices for Use in Oleds | BASF AKTIENGESELLSCHAFT (DE) | 2007-12-06 | — | — | US | disclosed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |
| US-20070225167-A1 | 2-Ethyl-4,6-Dimethyl-Phenyl-Substituted Tetramic Acid Derivatives as Pest Control Agents and/or Herbicides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-09-27 | — | — | US | disclosed |