SCHEMBL1480697

SCHEMBL1480697

Cc1ccccc1-c1cc(C(C)(C)C)cc2c1Cc1ccc(C(C)(C)C)cc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
CASP3 P42574 2/20 0.42
SENP8 Q96LD8 2/20 0.42
SENP7 Q9BQF6 2/20 0.42
SENP6 Q9GZR1 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
PLA2G1B P04054 1/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
KIF11 P52732 2/20 0.34
NR1H3 Q13133 1/20 0.33
ADORA1 P30542 1/20 0.33
CYP19A1 P11511 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18261204 0.85 ALDH1A1 (0.37) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL27989925 0.83 NPC1 (0.40) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL1480864 0.82 ALDH1A1 (0.41) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL3171441 0.79 ALDH1A1 (0.52) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL5680763 0.78 ALDH1A1 (0.55) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL27706427 0.77 GSTP1 (0.38) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL6471558 0.76 CYP1A2 (0.38) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL945914 0.76 ALDH1A1 (0.35) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL29556735 0.76 CYP1A2 (0.38) ALDH1A1CASP3SENP8SENP7SENP6
SCHEMBL30497613 0.76 ALDH1A1 (0.35) ALDH1A1CASP3SENP8SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103588917-B 4-methyl-1-pentene alpha-olefin copolymer and the composition containing this multipolymer MITSUI CHEMICAL INDUSTRY CO., LTD. (JP) 2015-10-14 CN disclosed
CN-101595176-B Propylene resin composition, method for producing propylene resin composition, propylene polymer composition, molded body made of the propylene resin composition, and electric wire MITSUI CHEMICALS INC 2014-06-18 CN disclosed
CN-102295721-B Process for producing syndiotactic alpha-olefin polymer MITSUI CHEMICALS INC 2013-04-17 CN disclosed
US-20110077369-A1 PROCESS FOR PREPARING OLEFIN POLYMER USING MIXED CATALYST MITSU CHEMICALS, INC. 2011-03-31 US disclosed
CN-101535384-A Polypropylene resin film and use thereof MITSUI CHEMICALS INC (JP) 2009-09-16 CN disclosed