SCHEMBL148088

SCHEMBL148088

NCC(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.44
GSTK1 Q9Y2Q3 1/20 0.44
GLO1 Q04760 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
PTGS2 P35354 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ECE1 P42892 5/20 0.37
GRIA1 P42261 1/20 0.35
GRIA3 P42263 1/20 0.35
MMP8 P22894 1/20 0.34
MME P08473 2/20 0.33
ACE P12821 1/20 0.33
CPA1 P15085 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
CTSC P53634 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29697132 1.00 PTGS1 (0.44) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL16094750 0.97 PTGS1 (0.43) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL901070 0.97 PTGS1 (0.43) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL6928953 0.97 PTGS1 (0.43) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL6129326 0.97 PTGS1 (0.43) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL7571502 0.95 PTGS1 (0.42) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL3493292 0.95 PTGS1 (0.42) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL8448660 0.95 PTGS1 (0.42) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL6136563 0.95 PTGS1 (0.42) PTGS1GSTK1GLO1ALDH1A1LMNA
SCHEMBL1472099 0.95 PTGS1 (0.42) PTGS1GSTK1GLO1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14018 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12516104-B2 Compositions and methods for diagnosis and treatment of cancer BioNTech SE (DE) 2026-01-06 US claimed
US-20240002471-A1 Compositions and Methods for Diagnosis and Treatment of Cancer BioNTech SE (DE) 2024-01-04 US claimed
CN-116987180-A Methods and compositions for cancer diagnosis and treatment 生物技术欧洲股份公司 2023-11-03 CN claimed
US-11673939-B2 Compositions and methods for diagnosis and treatment of cancer BioNTech SE 2023-06-13 US claimed
US-20210246191-A1 Compositions and Methods for Diagnosis and Treatment of Cancer BioNTech SE (DE) 2021-08-12 US claimed
EP-3802585-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CANCER BioNTech SE (DE) 2021-04-14 EP claimed
CN-112424220-A Methods and compositions for cancer diagnosis and treatment 生物技术欧洲股份公司 2021-02-26 CN claimed
WO-2019234190-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CANCER BioNTech SE (DE) 2019-12-12 WO claimed
WO-2019233605-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF CANCER BioNTech SE (DE) 2019-12-12 WO claimed
US-10370433-B2 Compositions and methods for diagnosis and treatment of cancer BIONTECH AG (DE) 2019-08-06 US claimed
WO-1991009870-A1 IMMUNOLOGICALLY ACTIVE PROTEINES FROM BORRELIA BURGDORFERI, RELATED TEST KITS AND VACCINE MIKROGEN MOLEKULARBIOLOGISCHE ENTWICKLUNGS-GMBH (DE) 1991-07-11 WO claimed
US-5030240-A Perhydrolysis; cleaning compounds THE CLOROX COMPANY (US) 1991-07-09 US claimed
WO-1991008310-A1 DETECTION OF HUMAN ADENOVIRUS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1991-06-13 WO claimed
WO-1991007419-A1 PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE GENE AND METHODS FOR ITS USE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1991-05-30 WO claimed
EP-0418310-A1 GENE FOR ENCODING A HUMAN MALARIA VACCINE ANTIGEN. US HEALTH (US) 1991-03-27 EP claimed
EP-0413440-A2 Peptidyl prolyl-cis.trans-isomerase Tonen Corporation (JP) 1991-02-20 EP claimed
WO-1989010936-A1 GENE FOR ENCODING A HUMAN MALARIA VACCINE ANTIGEN THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-11-16 WO claimed
US-4810492-A VACCINE AGAINST JAPANESE ENCEPHALITIS THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIVERSITY (JP) 1989-03-07 US claimed
US-4707358-A Vaccine against Epstein-Barr Virus THE UNIVERSITY OF CHICAGO (US) 1987-11-17 US claimed
US-4691009-A Hybrid proteins produced by an ultrahigh prokaryotic expression system REPLIGEN CORPORATION (US) 1987-09-01 US claimed