Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 5/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148088 | 1.00 | PTGS1 (0.44) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL16094750 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL901070 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL6928953 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL6129326 | 0.97 | PTGS1 (0.43) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL7571502 | 0.95 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL3493292 | 0.95 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL8448660 | 0.95 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL6136563 | 0.95 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA | |
| SCHEMBL1472099 | 0.95 | PTGS1 (0.42) | PTGS1GSTK1GLO1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250011367-A1 | CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | ENTRADA THERAPEUTICS, INC. | 2025-01-09 | — | — | US | disclosed |
| US-20220177523-A1 | CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | ENTRADA THERAPEUTICS, INC. | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250011367-A1 | CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | VIP, LNPEP, TAP1 | PTGS1 4293/4885GSTK1 3410/4885GLO1 4536/4885 |
| US-20220177523-A1 | CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | VIP, LNPEP, TAP1 | PTGS1 4293/4885GSTK1 3410/4885GLO1 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.