SCHEMBL148089

SCHEMBL148089

c1cc2cc3sc(-c4cc5cc6sccc6cc5s4)cc3cc2s1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.40
CYP2A6 P11509 2/20 0.39
ESR1 P03372 8/20 0.38
ESR2 Q92731 8/20 0.38
APP P05067 2/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
PTPRC P08575 1/20 0.33
PTPN6 P29350 1/20 0.33
PTPN11 Q06124 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.33
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
GPR35 Q9HC97 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23046405 0.90 APP (0.40) DYRK1ACYP2A6ESR1ESR2APP
SCHEMBL23556013 0.90 ESR1 (0.52) DYRK1ACYP2A6ESR1ESR2APP
SCHEMBL23556016 0.88 ESR1 (0.50) DYRK1AESR1ESR2APP
SCHEMBL23556012 0.88 ESR1 (0.50) DYRK1AESR1ESR2APP
SCHEMBL20625217 0.85 DYRK1A (0.53) DYRK1ACYP2A6ESR1ESR2APP
SCHEMBL17086827 0.85 ESR1 (0.57) DYRK1AESR1ESR2APPCTNNB1
SCHEMBL26500119 0.83 DYRK1A (0.37) DYRK1ACYP2A6ESR1ESR2ADORA2A
SCHEMBL26500333 0.83 DYRK1A (0.37) DYRK1ACYP2A6ESR1ESR2ADORA2A
SCHEMBL15087956 0.83 ESR1 (0.38) DYRK1ACYP2A6ESR1ESR2
SCHEMBL22025211 0.83 NPC1 (0.37) DYRK1ACYP2A6ESR1ESR2ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210119157-A1 SPUTTER PROTECTIVE LAYER FOR ORGANIC ELECTRONIC DEVICES SMARTKEM LIMITED (GB) 2021-04-22 US claimed
EP-1459392-B1 ORGANIC FIELD EFFECT TRANSISTOR WITH AN ORGANIC DIELECTRIC MERCK PATENT GMBH (DE) 2011-09-21 EP claimed
EP-2207217-A1 Organic field effect transistor with an organic dielectric Merck Patent GmbH (DE) 2010-07-14 EP claimed
EP-2204861-A1 Organic field effect transistor with an organic dielectric Merck Patent GmbH (DE) 2010-07-07 EP claimed
US-11882762-B2 Formulation and method for preparation of organic electronic devices FLEXENABLE TECHNOLOGY LIMITED (GB) 2024-01-23 US disclosed
US-20240008294-A1 ORGANIC THIN FILM TRANSISTOR SMARTKEM LIMITED (GB) 2024-01-04 US disclosed
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed
EP-4244909-A1 ORGANIC THIN FILM TRANSISTOR SmartKem Limited (GB) 2023-09-20 EP disclosed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP disclosed
EP-3323159-B1 COMPOSITION COMPRISING ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2023-01-04 EP disclosed
WO-2022101644-A1 ORGANIC THIN FILM TRANSISTOR SMARTKEM LIMITED (GB) 2022-05-19 WO disclosed
US-7029945-B2 Organic field effect transistor with an organic dielectric MERCK PATENT GMBH (DE) 2006-04-18 US disclosed
US-20050104058-A1 Organic field effect transistor with an organic dielectric MERCK PATENT GMBH (DE) 2005-05-19 US disclosed
EP-1529317-A2 ORGANIC ELECTRONIC DEVICES Avecia Limited (GB) 2005-05-11 EP disclosed
US-20040038459-A1 Field effect transistors and materials and methods for their manufacture MERCK PATENT GMBH (DE) 2004-02-26 US disclosed
WO-2004013922-A2 ORGANIC ELECTRONIC DEVICES AVECIA LIMITED (GB) 2004-02-12 WO disclosed
EP-1340270-A1 FIELD EFFECT TRANSISTORS AND MATERIALS AND METHODS FOR THEIR MANUFACTURE Avecia Limited (GB) 2003-09-03 EP disclosed
WO-2003052841-A1 ORGANIC FIELD EFFECT TRANSISTOR WITH AN ORGANIC DIELECTRIC AVECIA LIMITED (GB) 2003-06-26 WO disclosed
WO-2002045184-A1 FIELD EFFECT TRANSISTORS AND MATERIALS AND METHODS FOR THEIR MANUFACTURE AVECIA LIMITED (GB) 2002-06-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes JUP, L1CAM, EPCAM DYRK1A 3505/4885CYP2A6 3601/4885ESR1 560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.