SCHEMBL14809482

SCHEMBL14809482

CCC(O)(CC)C(O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPT2 P23786 1/20 0.43
ACLY P53396 1/20 0.43
TP53 P04637 1/20 0.36
CHRM1 P11229 1/20 0.35
AKR1A1 P14550 1/20 0.35
CHRM3 P20309 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GPR84 Q9NQS5 3/20 0.33
FFAR1 O14842 1/20 0.33
OR51E2 Q9H255 1/20 0.32
FFAR3 O14843 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23071625 0.77 CPT2 (0.41) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL42928 0.77 CPT2 (0.41) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL31072283 0.77 CPT2 (0.41) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL940317 0.77 CPT2 (0.41) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL940318 0.77 CPT2 (0.41) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL29706712 0.76 CPT2 (0.44) CPT2ACLYTP53OR51E2TSHR
SCHEMBL31390775 0.75 ACLY (0.61) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL9201113 0.75 ACLY (0.61) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL8277447 0.74 CPT2 (0.38) CPT2ACLYTP53CHRM1AKR1A1
SCHEMBL14661898 0.74 CPT2 (0.38) CPT2ACLYTP53CHRM1AKR1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013043801-A1 HIGH-PERFORMANCE DIHYDROXY ACID DEHYDRATASES GEVO, INC. (US) 2013-03-28 WO disclosed