SCHEMBL14809798

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16252243	0.90	CYP3A4 (0.36)	CYP3A4MAPTKMT2ADPP4LIPG
	SCHEMBL14823828	0.90	CYP3A4 (0.36)	CYP3A4KMT2ALIPGMMP2MMP9
	SCHEMBL14810084	0.89	CYP3A4 (0.36)	CYP3A4TP53LIPGMMP2MMP9
	SCHEMBL14809136	0.88	MAPT (0.37)	CYP3A4TP53MAPTKMT2ALIPG
	SCHEMBL14810111	0.86	MAPT (0.39)	CYP3A4TP53MAPTLIPG
	SCHEMBL14810135	0.85	CYP3A4 (0.34)	CYP3A4LIPGP2RX3PSIP1
	SCHEMBL16252239	0.85	CYP3A4 (0.34)	CYP3A4LIPGP2RX3PSIP1
	SCHEMBL14809836	0.85	MAPT (0.36)	CYP3A4TP53MAPTKMT2A
	SCHEMBL14810628	0.85	MEN1 (0.34)	CYP3A4KMT2A
	SCHEMBL16252244	0.84	CYP3A4 (0.36)	CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.