SCHEMBL14814830

SCHEMBL14814830

ClC1(c2ccccc2)C(CC2=Cc3ccccc3C2(Cl)c2ccccc2)=Cc2ccccc21.[Hf]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14815254 0.96
SCHEMBL7642471 0.75
SCHEMBL11453271 0.69 CFTR (0.37)
SCHEMBL7518292 0.67
SCHEMBL6058448 0.65
SCHEMBL27933311 0.64 CYP2D6 (0.33)
SCHEMBL11510200 0.63 S100A4 (0.45)
SCHEMBL7528738 0.63
SCHEMBL18281517 0.61 CYP2C9 (0.34)
SCHEMBL27948787 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US claimed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP claimed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US claimed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO claimed
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US disclosed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP disclosed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US disclosed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO disclosed