Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 19/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 19/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260082 | 1.00 | CYP11B1 (0.52) | CYP11B1CYP11B2 | |
| SCHEMBL21535358 | 0.86 | CYP11B1 (0.53) | CYP11B1CYP11B2 | |
| SCHEMBL31259993 | 0.86 | CYP11B2 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL14789968 | 0.86 | CYP11B2 (0.49) | CYP11B1CYP11B2 | |
| SCHEMBL31259945 | 0.86 | CYP11B1 (0.53) | CYP11B1CYP11B2 | |
| SCHEMBL31260070 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2 | |
| SCHEMBL14789887 | 0.85 | CYP11B1 (0.54) | CYP11B1CYP11B2 | |
| SCHEMBL14789998 | 0.83 | CYP11B1 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL14789959 | 0.80 | CYP11B2 (0.48) | CYP11B1CYP11B2 | |
| SCHEMBL14816649 | 0.80 | CYP11B1 (0.64) | CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-A1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2020-05-20 | — | — | EP | disclosed |
| EP-2755963-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2019-10-30 | — | — | EP | disclosed |
| WO-2013037779-A1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-21 | — | — | WO | disclosed |