Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.34 |
| ▸ | CDC25B | P30305 | 5/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12243178 | 0.92 | PDE2A (0.35) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL20477154 | 0.92 | PDE2A (0.35) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL20553048 | 0.92 | PDE2A (0.35) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL29727834 | 0.92 | PDE2A (0.35) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL17712276 | 0.92 | PDE2A (0.35) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL27086511 | 0.92 | PDE2A (0.35) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL24158032 | 0.90 | PDE2A (0.38) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL22646505 | 0.90 | PDE2A (0.38) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| Maleic Acid SCHEMBL20552110 | 0.86 | TMPRSS2 (0.36) | HSPA5PTPN1CDC25BPDE2ATMPRSS2 | |
| SCHEMBL31725309 | 0.86 | PDE2A (0.36) | HSPA5PDE2ATMPRSS2TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709613-B1 | METHODS FOR TREATING HCV | GILEAD PHARMASSET LLC (US) | 2017-11-29 | — | — | EP | disclosed |
| WO-2013040492-A2 | METHODS FOR TREATING HCV | GILEAD SCIENCES, INC. (US) | 2013-03-21 | — | — | WO | disclosed |