Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | MDH1 | P40925 | 1/20 | 0.34 |
| ▸ | MDH2 | P40926 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352776 | 0.93 | ADORA3 (0.46) | ADORA3SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL253891 | 0.89 | ADORA3 (0.47) | ADORA3SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL13168810 | 0.88 | ADORA3 (0.55) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL14817446 | 0.82 | MAPT (0.42) | MDH1MDH2MAPTTDP1KMT2A | |
| SCHEMBL15084063 | 0.80 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL10046812 | 0.79 | ADORA3 (0.60) | ADORA3SLC6A2SLC6A4SLC6A3MAPT | |
| SCHEMBL12352822 | 0.79 | ADORA3 (0.55) | ADORA3SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL13328173 | 0.78 | ADORA3 (0.55) | ADORA3SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL14817468 | 0.78 | ADORA3 (0.50) | ADORA3SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL10030680 | 0.77 | ADORA3 (0.57) | ADORA3SLC6A2SLC6A4SLC6A3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404414-B2 | Electrophotographic photoconductor and manufacturing method thereof | FUJI ELECTRIC CO., LTD. (JP) | 2013-03-26 | — | — | US | disclosed |