SCHEMBL14817756

CO[C@H]1OC(COS(=O)(=O)O)[C@@H](O[C@@H]2OC(C(=O)O)[C@H](O[C@@H]3OC(COS(=O)(=O)O)[C@@H](O[C@@H]4OC(C(=O)O)[C@@H](O[C@H]5OC(COS(=O)(=O)O)[C@@H](O)[C@H](O)C5C)C(O)[C@@H]4O)[C@H](OS(=O)(=O)O)C3C)C(O)[C@@H]2OS(=O)(=O)O)[C@H](O)C1C

nearest known ligand 0.69

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	6/20	0.69

▸	SERPINC1	P01008	3/20	0.52

▸	FGF1	P05230	3/20	0.48

▸	BDNF	P23560	3/20	0.44

▸	PTN	P21246	2/20	0.44

▸	MDK	P21741	2/20	0.44

▸	CXCL10	P02778	1/20	0.42

▸	CXCL8	P10145	1/20	0.42

▸	CCL2	P13500	1/20	0.42

▸	CCL5	P13501	1/20	0.42

▸	CXCL12	P48061	1/20	0.42

▸	F2	P00734	1/20	0.41

▸	HPSE	Q9Y251	4/20	0.38

▸	FGF2	P09038	1/20	0.37

▸	PF4	P02776	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16656905	0.91	F10 (0.63)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16330427	0.91	F10 (0.71)	F10SERPINC1FGF1BDNFPTN
SCHEMBL12360709	0.89	F10 (0.62)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16418325	0.89	F10 (0.60)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16656904	0.88	F10 (0.60)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16656848	0.88	F10 (0.60)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16425607	0.86	F10 (0.58)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16425614	0.86	F10 (0.57)	F10SERPINC1FGF1BDNFPTN
SCHEMBL18061224	0.86	F10 (0.57)	F10SERPINC1FGF1BDNFPTN
SCHEMBL16425612	0.86	F10 (0.58)	F10SERPINC1FGF1BDNFPTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8404833-B2	Synthetic heparin disaccharides	ALCHEMIA LIMITED (AU)	2013-03-26	—	—	US	disclosed