SCHEMBL16656905

CO[C@H]1OC(COS(=O)(=O)O)[C@H](O[C@@H]2OC(C(=O)O)[C@H](O[C@@H]3OC(COS(=O)(=O)O)[C@H](O[C@@H]4OC(C(=O)O)[C@H](O[C@@H]5OC(COS(=O)(=O)O)[C@H](O[C@@H]6OC(C(=O)O)[C@H](O[C@@H]7OC(COS(=O)(=O)O)[C@H](O[C@@H]8OC(C(=O)O)[C@@H](O)C(O)[C@@H]8OS(=O)(=O)O)C(O)[C@@H]7C)C(O)[C@@H]6OS(=O)(=O)O)C(O)[C@@H]5C)C(O)[C@@H]4OS(=O)(=O)O)C(O)[C@@H]3C)C(O)[C@@H]2OS(=O)(=O)O)C(O)[C@@H]1C

nearest known ligand 0.63

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	7/20	0.63

▸	SERPINC1	P01008	2/20	0.54

▸	BDNF	P23560	3/20	0.48

▸	PTN	P21246	2/20	0.48

▸	MDK	P21741	2/20	0.48

▸	CXCL12	P48061	2/20	0.46

▸	CXCL10	P02778	1/20	0.46

▸	CXCL8	P10145	1/20	0.46

▸	CCL2	P13500	1/20	0.46

▸	CCL5	P13501	1/20	0.46

▸	FGF1	P05230	4/20	0.46

▸	FGF2	P09038	1/20	0.40

▸	BMP2	P12643	1/20	0.40

▸	VEGFA	P15692	1/20	0.40

▸	SHH	Q15465	1/20	0.40

▸	HPSE	Q9Y251	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16656904	0.96	F10 (0.60)	F10SERPINC1BDNFPTNMDK
SCHEMBL16656848	0.96	F10 (0.60)	F10SERPINC1BDNFPTNMDK
SCHEMBL12360709	0.94	F10 (0.62)	F10SERPINC1BDNFPTNMDK
SCHEMBL14817756	0.91	F10 (0.69)	F10SERPINC1BDNFPTNMDK
SCHEMBL15417563	0.86	F10 (0.53)	F10SERPINC1BDNFPTNMDK
SCHEMBL16425614	0.86	F10 (0.57)	F10SERPINC1BDNFPTNMDK
SCHEMBL16425612	0.86	F10 (0.58)	F10SERPINC1BDNFPTNMDK
SCHEMBL16425619	0.86	F10 (0.57)	F10SERPINC1BDNFPTNMDK
SCHEMBL16418325	0.86	F10 (0.60)	F10SERPINC1BDNFPTNMDK
SCHEMBL16656874	0.83	F10 (0.52)	F10SERPINC1BDNFPTNMDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9012413-B2	FGF receptor-activating N-acyl octasaccharides, preparation thereof, and therapeutic use thereof	SANOFI (FR)	2015-04-21	—	—	US	disclosed