Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | PHGDH | O43175 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507464 | 0.82 | RXFP1 (0.47) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL11888197 | 0.82 | RXFP1 (0.47) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL15045011 | 0.77 | RXFP1 (0.46) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL1253301 | 0.76 | RXFP1 (0.72) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL15045013 | 0.75 | F10 (0.52) | F10 | |
| SCHEMBL15045075 | 0.73 | F10 (0.70) | F10 | |
| SCHEMBL1857427 | 0.73 | SMYD3 (0.67) | F10 | |
| SCHEMBL13378793 | 0.73 | SMYD3 (0.67) | F10 | |
| SCHEMBL5371698 | 0.73 | SMYD3 (0.67) | F10 | |
| SCHEMBL13415456 | 0.72 | RXFP1 (0.62) | RXFP1AHRPHGDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405852-B9 | DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2013-03-27 | — | — | EP | disclosed |