Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4093939 | 0.81 | F10 (0.57) | F10F2 | |
| SCHEMBL5902829 | 0.81 | F10 (0.57) | F10F2 | |
| SCHEMBL14817845 | 0.77 | RXFP1 (0.56) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL11888214 | 0.73 | HTR1A (0.33) | MEN1KMT2AF10F2 | |
| SCHEMBL15045075 | 0.73 | F10 (0.70) | F10F2 | |
| SCHEMBL47199 | 0.69 | RXFP1 (0.52) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL42264 | 0.69 | RXFP1 (0.52) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL13151484 | 0.69 | RXFP1 (0.52) | RXFP1AHRPHGDHMEN1KMT2A | |
| SCHEMBL15045009 | 0.68 | F10 (0.58) | F10F2 | |
| SCHEMBL1253301 | 0.67 | RXFP1 (0.72) | RXFP1AHRPHGDHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2431370-B1 | Monoacylated 1,2-diaminocycloalkanes | DAIICHI SANKYO CO LTD (JP) | 2013-06-19 | — | — | EP | disclosed |