Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619618 | 0.74 | NPC1 (0.41) | ALDH1A1KDM4EMEN1KMT2ACASR | |
| SCHEMBL622163 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2ACASR | |
| SCHEMBL621872 | 0.71 | NPC1 (0.55) | ALDH1A1KDM4EMEN1KMT2ACASR | |
| SCHEMBL24576223 | 0.66 | NPC1 (0.71) | ALDH1A1KDM4EMEN1KMT2ACASR | |
| SCHEMBL16562080 | 0.63 | NPC1 (0.77) | ALDH1A1KDM4EMEN1KMT2ACASR | |
| SCHEMBL23747385 | 0.63 | SMN1; SMN2 (0.70) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL23728254 | 0.62 | SMN1; SMN2 (0.68) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL26100519 | 0.62 | SMN1; SMN2 (0.68) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1567200 | 0.62 | HDAC1 (0.59) | KMT2ASMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL20402350 | 0.61 | ANPEP (0.67) | ALDH1A1KDM4EMEN1KMT2ACASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2573559-A1 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |