SCHEMBL14818397 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DHFR	P00374	2/20	0.41

▸	HTR2A	P28223	1/20	0.39

▸	FFAR4	Q5NUL3	8/20	0.38

▸	CCR8	P51685	2/20	0.33

▸	KCNH2	Q12809	2/20	0.33

▸	KMT2A	Q03164	1/20	0.32

▸	LMNA	P02545	1/20	0.31

▸	KDM5A	P29375	1/20	0.30

▸	KDM4C	Q9H3R0	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12035969	0.82	FFAR4 (0.39)	DHFRHTR2AFFAR4KMT2AKDM5A
SCHEMBL12035983	0.82	FFAR4 (0.39)	DHFRHTR2AFFAR4KMT2ALMNA
SCHEMBL2437696	0.81	FFAR4 (0.38)	DHFRHTR2AFFAR4KMT2ALMNA
SCHEMBL12035998	0.81	HTR2A (0.39)	DHFRHTR2AFFAR4KMT2ALMNA
SCHEMBL12056189	0.81	FFAR4 (0.38)	DHFRHTR2AFFAR4KMT2ALMNA
SCHEMBL12035510	0.81	FFAR4 (0.54)	DHFRHTR2AFFAR4
SCHEMBL12035976	0.79	DHFR (0.45)	DHFRHTR2AFFAR4KMT2ALMNA
SCHEMBL12036054	0.78	FFAR4 (0.39)	DHFRHTR2AFFAR4KMT2AKDM5A
SCHEMBL12035992	0.78	FFAR4 (0.37)	DHFRHTR2AFFAR4KMT2ALMNA
SCHEMBL9983136	0.76	GAA (0.36)	DHFRHTR2AFFAR4KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2367793-B1	GPR120 RECEPTOR AGONISTS AND USES THEREOF	METABOLEX INC (US)	2013-03-27	—	—	EP	disclosed