Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034856 | 0.85 | HTR2A (0.49) | HTR2AFFAR4PKMNPSR1CTSA | |
| SCHEMBL28823607 | 0.83 | HTR2A (0.47) | HTR2AFFAR4PKMNPSR1GABRA1 | |
| SCHEMBL4750485 | 0.78 | HTR2A (0.51) | HTR2AFFAR4PKMNPSR1LMNA | |
| SCHEMBL18768202 | 0.76 | HTR2A (0.52) | HTR2AFFAR4PKMNPSR1 | |
| SCHEMBL1005341 | 0.75 | HTR2A (0.51) | HTR2AFFAR4PKMNPSR1 | |
| SCHEMBL1007650 | 0.75 | HTR2A (0.55) | HTR2AFFAR4PKMNPSR1 | |
| SCHEMBL12035510 | 0.74 | FFAR4 (0.54) | HTR2AFFAR4PKMNPSR1CTSA | |
| SCHEMBL220746 | 0.73 | PKM (0.50) | HTR2AFFAR4PKMNPSR1LMNA | |
| SCHEMBL17449704 | 0.73 | HTR2A (0.50) | HTR2AFFAR4PKMNPSR1CTSA | |
| SCHEMBL7626504 | 0.73 | HTR2A (0.50) | HTR2AFFAR4PKMNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367793-B1 | GPR120 RECEPTOR AGONISTS AND USES THEREOF | METABOLEX INC (US) | 2013-03-27 | — | — | EP | disclosed |