Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GUSB | P08236 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14804388 | 0.88 | NPC1 (0.53) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL2274986 | 0.86 | NPC1 (0.76) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL2278530 | 0.85 | NPC1 (1.00) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL1423255 | 0.84 | NPC1 (0.61) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4929292 | 0.84 | NPC1 (0.73) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL12145548 | 0.84 | CYP2A6 (0.65) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL17055536 | 0.82 | CYP2A6 (0.62) | ALDH1A1CYP1A2CYP3A4CYP2C19CA2 | |
| SCHEMBL1423264 | 0.82 | NPC1 (0.73) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL13002609 | 0.81 | RAB9A (0.70) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL1422922 | 0.81 | NPC1 (0.69) | NPC1RAB9AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130075714-A1 | POLYMER, POLYMER COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE | SUMTOMO CHEMICAL COMPANY LIMITED (JP) | 2013-03-28 | — | — | US | disclosed |