SCHEMBL14819160

SCHEMBL14819160

C=CCO[C@H]1OC(CO[C@]2(C(=O)OC)C[C@@H](O)[C@@H](NC(C)=O)C([C@H](O)[C@H](O)CO)O2)[C@H](O)[C@H](O)C1NC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAG P20916 6/20 0.52
▸ SIGLEC7 Q9Y286 4/20 0.51
▸ NANP Q8TBE9 1/20 0.47
▸ CD22 P20273 8/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18934902 1.00 MAG (0.52) MAGSIGLEC7NANPCD22
SCHEMBL14819210 0.93 SIGLEC7 (0.57) MAGSIGLEC7CD22
SCHEMBL14865175 0.93 SIGLEC7 (0.57) MAGSIGLEC7CD22
SCHEMBL18934784 0.88 MAG (0.47) MAGSIGLEC7CD22
SCHEMBL14819216 0.88 MAG (0.47) MAGSIGLEC7CD22
SCHEMBL14819161 0.86 SIGLEC7 (0.53) MAGSIGLEC7CD22
SCHEMBL18934901 0.86 SIGLEC7 (0.53) MAGSIGLEC7CD22
SCHEMBL14819157 0.86 SIGLEC7 (0.51) MAGSIGLEC7CD22
SCHEMBL15087687 0.85 NANP (0.58) MAGSIGLEC7NANPCD22
SCHEMBL16839997 0.85 NANP (0.58) MAGSIGLEC7NANPCD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9695208-B2 Sialic acid (A-(2-6))-D-aminopyranose derivatives, synthesis methods and uses thereof PEKING UNIVERSITY (CN) 2017-07-04 — — US disclosed
EP-2581380-A1 SIALIC ACID ( -(2 6)-D-AMINOPYRANOSE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF Peking University (CN) 2013-04-17 — — EP disclosed
US-20130079291-A1 SIALIC ACID (A-(2-6))-D-AMINOPYRANOSE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF PEKING UNIVERSITY (CN) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130079291-A1 SIALIC ACID (A-(2-6))-D-AMINOPYRANOSE DERIVATIVES, SYNTHESIS METHODS AND USES THEREOF ST6GAL1, FUT6, B3GNT2 MAG 453/4885SIGLEC7 14/4885NANP 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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