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FUT6

4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6 · P51993 · FUT6 on Sugi Atlas →

749 patent compounds predicted against FUT6, 333 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL16252063 SCHEMBL16252063 0.77 4/20
SCHEMBL25900152 SCHEMBL25900152 0.61 4/20
SCHEMBL26622682 SCHEMBL26622682 0.58 4/20
SCHEMBL25891143 SCHEMBL25891143 0.57 4/20
SCHEMBL25899071 SCHEMBL25899071 0.57 4/20
SCHEMBL26561375 SCHEMBL26561375 0.55 4/20
SCHEMBL22001331 SCHEMBL22001331 0.54 4/20
SCHEMBL25891136 SCHEMBL25891136 0.54 4/20
SCHEMBL25898913 SCHEMBL25898913 0.54 4/20
SCHEMBL25898915 SCHEMBL25898915 0.54 4/20
SCHEMBL25893244 SCHEMBL25893244 0.53 4/20
SCHEMBL14178471 SCHEMBL14178471 0.52 4/20
SCHEMBL14178455 SCHEMBL14178455 0.51 4/20
SCHEMBL26622038 SCHEMBL26622038 0.51 4/20
SCHEMBL25892921 SCHEMBL25892921 0.51 4/20
SCHEMBL25962155 SCHEMBL25962155 0.51 4/20
SCHEMBL25962157 SCHEMBL25962157 0.51 4/20
SCHEMBL25962871 SCHEMBL25962871 0.51 4/20
SCHEMBL25964112 SCHEMBL25964112 0.51 4/20
SCHEMBL18763248 SCHEMBL18763248 0.50 4/20

Clinical trials — most relevant to FUT6 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
BEFORE Study, Efficacy of Refigura PHASE4COMPLETED
A Safety and Efficacy Study of Fabrazyme® Replacement Therapy in Patients With Cardiac Fabry Disease PHASE4COMPLETED
Monosialoganglioside in Acute Ischemic Stroke: a Randomized, Blinded and Multicenter Confirmatory Study PHASE3COMPLETED
Multi-Center Study of ManNAc for GNE Myopathy PHASE2ACTIVE_NOT_RECRUITING
An Open-Label Phase 2 Study of N-Acetyl-D-Mannosamine (ManNAc) in Subjects With Primary Focal Segmental Glomerulosclerosis PHASE2RECRUITING
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis PHASE1/PHASE2RECRUITING
Oral N-acetylglucosamine in Crohn's Disease PHASE2NOT_YET_RECRUITING
Efficacy of Monosialotetrahexosylganglioside in the Prophylactic Treatment of Bortezomib-induced Peripheral Neuropathy PHASE2UNKNOWN
A Study of GlcNAc on Tear Production in NGLY1-CDDG PHASE2ACTIVE_NOT_RECRUITING
Vaccine Treatment for Surgically Resected Pancreatic Cancer PHASE1/PHASE2COMPLETED
Vaccine Treatment for Advanced Non-Small Cell Lung Cancer PHASE1/PHASE2COMPLETED
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects With Primary Podocyte Diseases PHASE1COMPLETED
Autologous Stem Cell Transplantation of Cells Engineered to Express Alpha-Galactosidase A in Patients With Fabry Disease PHASE1COMPLETED
Vaccine Therapy Plus Biological Therapy in Treating Patients With Prostate Cancer PHASE1COMPLETED
Intravenous Immune Globulin to Treat Hereditary Inclusion Body Myopathy PHASE1COMPLETED
Phase I Norovirus Challenge Model PHASE1COMPLETED
Glycosylation in Patients With Galactosaemia nanCOMPLETED
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption nanUNKNOWN
Sialic Acid Supplementation in N-Acetylneuraminic Acid Synthase (NANS) Deficiency nanCOMPLETED
A Retrospective Study to Identify New Omics Biomarkers of Chronic/Persistent Low Back Pain nanCOMPLETED
Biomarker for Mucolipidosis Disorder Type I, II, III, IV (BioML) nanWITHDRAWN
The Natural History of Alpha-Mannosidosis nanCOMPLETED
A Clinical Study to Assess the Effect of Increasing Intake Amounts of Two Novel Glycans on the Gut Microbiota of Healthy Subjects nanCOMPLETED
Biomarker for Gangliosidosis: BioGM1/BioGM2 (BioGM1/GM2) nanWITHDRAWN
Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites nanCOMPLETED
GI Alpha-Gal Study nanCOMPLETED
Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing nanUNKNOWN
Polyglucosamine L112 in Overweight and Obese Subjects nanCOMPLETED
Registry Gangliosidoses nanUNKNOWN
Glycan Attachment Specificity, Toward ROtavirus Vaccine IMprovement GASTROVIMc (Clinical Investigation) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a FUT6 binder may also engage these)

ProteinNameSimilarity
P56434 — 1.000 P56434 →
Q9GKU6 — 1.000 Q9GKU6 →
Q8HYJ3 — 1.000 Q8HYJ3 →
Q8HYJ6 — 1.000 Q8HYJ6 →
O19058 — 1.000 O19058 →
Q8HYJ7 — 1.000 Q8HYJ7 →
Q8HYJ5 — 0.999 Q8HYJ5 →
P56433 — 0.999 P56433 →
Q11126 — 0.997 Q11126 →
Q8HYJ4 — 0.996 Q8HYJ4 →
FUT5 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5 0.996 landscape →
P21217 — 0.994 P21217 →
Q712G6 — 0.990 Q712G6 →
Q8HZR3 — 0.983 Q8HZR3 →
Q11131 — 0.983 Q11131 →
Q62994 — 0.980 Q62994 →
FUT7 Alpha-(1,3)-fucosyltransferase 7 0.977 landscape →
Q11127 — 0.973 Q11127 →
G3MZR2 — 0.973 G3MZR2 →
Q6A198 — 0.970 Q6A198 →
O09008 — 0.969 O09008 →
Q29043 — 0.969 Q29043 →
Q5F2L1 — 0.968 Q5F2L1 →
Q866D9 — 0.968 Q866D9 →
Q866C7 — 0.966 Q866C7 →
Q866E6 — 0.966 Q866E6 →
Q9JKV7 — 0.966 Q9JKV7 →
Q10980 — 0.965 Q10980 →
Q92935 — 0.965 Q92935 →
Q866D2 — 0.965 Q866D2 →