SCHEMBL14819894

SCHEMBL14819894

CN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O)C(=O)O)C(N)=O

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.68
▸ CCKAR P32238 12/20 0.48
▸ CCKBR P32239 12/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13577532 0.99 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL15002881 0.95 GLP1R (0.62) GLP1RCCKARCCKBR
SCHEMBL15579830 0.94 GLP1R (0.72) GLP1RCCKARCCKBR
SCHEMBL19786713 0.94 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL21242874 0.94 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL17127184 0.94 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL21242938 0.94 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL21242749 0.94 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL21242892 0.94 GLP1R (0.69) GLP1RCCKARCCKBR
SCHEMBL14805474 0.94 GLP1R (0.69) GLP1RCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160347812-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2016-12-01 — — US disclosed
US-20150374794-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE NOVO NORDISK A/S (DK) 2015-12-31 — — US disclosed
US-20130079278-A1 Novel Glucagon Analogues NOVO NORDISK A/S (DK) 2013-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150374794-A1 STABLE, PROTRACTED GLP-1/GLUCAGON RECEPTOR CO-AGONISTS FOR MEDICAL USE GLP1R, GIPR, GCGR GLP1R 1/4885CCKAR 24/4885CCKBR 21/4885
US-20130079278-A1 Novel Glucagon Analogues GLP1R, GCG, GCGR GLP1R 1/4885CCKAR 64/4885CCKBR 34/4885
US-20160347812-A1 Novel Glucagon Analogues GLP1R, GCG, GCGR GLP1R 1/4885CCKAR 64/4885CCKBR 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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