Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.32 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618932 | 0.84 | FSCN1 (0.44) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4154186 | 0.83 | LMNA (0.37) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4142022 | 0.83 | PTPRZ1 (0.37) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4149723 | 0.81 | TSHR (0.38) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4142460 | 0.80 | LMNA (0.35) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4150851 | 0.79 | PTPRZ1 (0.36) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4158539 | 0.77 | MAPT (0.36) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4149940 | 0.77 | PTPRZ1 (0.35) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4144820 | 0.77 | PTPRZ1 (0.35) | TSHRLMNAMAPTMAPK1HTT | |
| SCHEMBL4149965 | 0.77 | ACKR3 (0.38) | MAPK1HTTPTPRZ1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2174929-B1 | 4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE | SUMITOMO CHEMICAL CO (JP) | 2013-03-27 | — | — | EP | disclosed |