Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274611 | 0.97 | CNR2 (0.41) | CNR1CNR2CYP2C9KMT2AKDM4E | |
| SCHEMBL10208163 | 0.92 | ALDH1A1 (0.40) | CNR1CNR2KMT2AKDM4EHTR1B | |
| SCHEMBL29708064 | 0.88 | CNR1 (0.41) | CNR1CNR2CYP2C9KMT2AKDM4E | |
| SCHEMBL28459943 | 0.88 | CNR1 (0.41) | CNR1CNR2CYP2C9KMT2AKDM4E | |
| SCHEMBL28459946 | 0.88 | CNR1 (0.41) | CNR1CNR2CYP2C9KMT2AKDM4E | |
| SCHEMBL1273006 | 0.88 | BTN3A1 (0.45) | L3MBTL1ALDH1A1HPGD | |
| SCHEMBL14941789 | 0.87 | ALDH1A1 (0.39) | KMT2AKDM4EHTR1BNR2E1ALDH1A1 | |
| SCHEMBL14941788 | 0.87 | ALDH1A1 (0.39) | KMT2AKDM4EHTR1BNR2E1ALDH1A1 | |
| SCHEMBL723663 | 0.86 | BTN3A1 (0.39) | KMT2AKDM4EHTR1BNR2E1ALDH1A1 | |
| SCHEMBL723664 | 0.86 | BTN3A1 (0.39) | KMT2AKDM4EHTR1BNR2E1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013044030-A1 | 2'-CHLOROACETYLENYL SUBSTITUTED NUCLEOSIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2013-03-28 | — | — | WO | disclosed |