Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822514 | 1.00 | PDK2 (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL12699710 | 1.00 | PDK2 (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL14960765 | 1.00 | PDK2 (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL14822254 | 1.00 | PDK2 (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL10001350 | 0.99 | PGR (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL10001471 | 0.99 | PGR (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL14822250 | 0.98 | PDK2 (0.33) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL12292006 | 0.98 | PDK2 (0.33) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL10001519 | 0.97 | PGR (0.35) | PDK2PGRKDM4EATML3MBTL1 | |
| SCHEMBL10001497 | 0.97 | PGR (0.35) | PDK2PGRKDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-9818948-B2 | Carbazole derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140225046-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| WO-2013041176-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2013-03-28 | — | — | WO | disclosed |