Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 13/20 | 0.79 |
| ▸ | PRKCD | Q05655 | 10/20 | 0.79 |
| ▸ | PRKD3 | O94806 | 10/20 | 0.79 |
| ▸ | PRKCG | P05129 | 10/20 | 0.79 |
| ▸ | PRKCZ | Q05513 | 10/20 | 0.79 |
| ▸ | PRKCB | P05771 | 9/20 | 0.79 |
| ▸ | PRKCA | P17252 | 9/20 | 0.79 |
| ▸ | PRKCH | P24723 | 9/20 | 0.79 |
| ▸ | PRKCI | P41743 | 9/20 | 0.79 |
| ▸ | PRKCE | Q02156 | 9/20 | 0.79 |
| ▸ | PRKD1 | Q15139 | 9/20 | 0.79 |
| ▸ | PRKACA | P17612 | 8/20 | 0.79 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.79 |
| ▸ | PRKACG | P22612 | 7/20 | 0.79 |
| ▸ | PRKACB | P22694 | 7/20 | 0.79 |
| ▸ | EGFR | P00533 | 5/20 | 0.79 |
| ▸ | SRC | P12931 | 5/20 | 0.79 |
| ▸ | FLT3 | P36888 | 4/20 | 0.70 |
| ▸ | PIM1 | P11309 | 3/20 | 0.70 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260178 | 0.89 | PRKCQ (0.81) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL12253230 | 0.89 | PRKCQ (0.81) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL12253229 | 0.89 | PRKCQ (0.81) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL29711605 | 0.88 | PRKCQ (1.00) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL14822789 | 0.88 | PRKCQ (1.00) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL12570345 | 0.82 | PIM1 (1.00) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL12570347 | 0.82 | PIM1 (1.00) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL29818137 | 0.82 | PIM1 (1.00) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL22765429 | 0.81 | PRKCQ (0.83) | PRKCQPRKCDPRKD3PRKCGPRKCZ | |
| SCHEMBL638600 | 0.81 | PRKCQ (0.83) | PRKCQPRKCDPRKD3PRKCGPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410267-B2 | Regioselective reduction of fused pyrrolocarbazoles-5,7-diones | TEVA SANTE (FR) | 2013-04-02 | — | — | US | disclosed |