SCHEMBL14822728

SCHEMBL14822728

Cc1ccc2c(c1)CCN2c1cc(OC2CCN(C(=O)OC(C)(C)C)CC2)ncn1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515184 0.91 GPR119 (0.61) GPR119
SCHEMBL1065558 0.90 GPR119 (0.60) GPR119
SCHEMBL515571 0.90 GPR119 (0.59) GPR119
SCHEMBL1065262 0.88 GPR119 (0.79) GPR119
SCHEMBL3238881 0.87 GPR119 (0.59) GPR119
SCHEMBL515580 0.87 GPR119 (0.59) GPR119
SCHEMBL3240830 0.87 GPR119 (0.68) GPR119
SCHEMBL3246004 0.87 GPR119 (0.67) GPR119
SCHEMBL3245045 0.87 GPR119 (0.67) GPR119
SCHEMBL3240103 0.86 GPR119 (0.71) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410089-B2 Fused heterocyclic ring compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-04-02 US disclosed