Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704915 | 0.72 | KMT2A (0.66) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13546239 | 0.71 | MAPT (0.63) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL16938818 | 0.71 | MAPT (0.63) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL171043 | 0.71 | DGAT1 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10227621 | 0.71 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL174525 | 0.70 | ATM (0.44) | ALDH1A1MAPTKMT2AMEN1L3MBTL1 | |
| SCHEMBL15176788 | 0.69 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL13546278 | 0.68 | HPGD (0.43) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL10747787 | 0.68 | MAPT (0.62) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL28964071 | 0.68 | MAPT (0.62) | ALDH1A1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410155-B2 | Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIA inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-02 | — | — | US | disclosed |