Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.68 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.59 |
| ▸ | MLNR | O43193 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487018 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL2487343 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL1417436 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL9407088 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL11252092 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL1408157 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL11408805 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL11084816 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL2052458 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 | |
| SCHEMBL7923425 | 1.00 | LTA4H (0.68) | LTA4HKCNA3MLNRNR1I2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030082206-A1 | Method of preserving infectious recombinant viruses, aqueous viral suspension, and use as medicament | SENE CLAUDE (FR) | 2003-05-01 | — | — | US | claimed |
| US-6451256-B1 | RECOMBINANT VIRUSES IN FROZEN OR LIQUID FORM, IN WHICH INFECTIOUS VIRUSES ARE PRESERVED IN AN AQUEOUS SOLUTION. THE RECOMBINANT VIRUS SUSPENSION COMPRISES AN AQUEOUS SUCROSE SOLUTION AT A CONCENTRATION FOR GENE THERAPY. | TRANSGENE S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| US-9012198-B2 | Method for orthopoxvirus production and purification | TRANSGENE S.A. (FR) | 2015-04-21 | — | — | US | disclosed |
| US-20140073033-A1 | METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION | TRANSGENE S.A. (FR) | 2014-03-13 | — | — | US | disclosed |
| US-8609392-B2 | Method for orthopoxvirus production and purification | TRANSGENE S.A. (FR) | 2013-12-17 | — | — | US | disclosed |
| EP-2429580-A1 | METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION | Transgene SA (FR) | 2012-03-21 | — | — | EP | disclosed |
| US-20120058539-A1 | METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION | TRANSGENE S.A. (FR) | 2012-03-08 | — | — | US | disclosed |
| WO-2010130753-A1 | METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION | TRANSGENE SA (FR) | 2010-11-18 | — | — | WO | disclosed |
| US-6451256-B1 | RECOMBINANT VIRUSES IN FROZEN OR LIQUID FORM, IN WHICH INFECTIOUS VIRUSES ARE PRESERVED IN AN AQUEOUS SOLUTION. THE RECOMBINANT VIRUS SUSPENSION COMPRISES AN AQUEOUS SUCROSE SOLUTION AT A CONCENTRATION FOR GENE THERAPY. | TRANSGENE S.A. (FR) | 2002-09-17 | — | — | US | disclosed |