Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663990 | 0.87 | TDP1 (0.57) | TDP1CTDSP1EPHX1ALDH1A1MAPT | |
| SCHEMBL8296751 | 0.77 | EPHX1 (0.68) | TDP1CTDSP1EPHX1ALDH1A1MAPT | |
| SCHEMBL8612483 | 0.73 | EPHX1 (0.77) | TDP1EPHX1ALDH1A1MAPTRAB9A | |
| SCHEMBL4365347 | 0.73 | KMT2A (0.54) | TDP1CTDSP1EPHX1ALDH1A1MAPT | |
| SCHEMBL2338840 | 0.72 | PPIA (0.61) | RAB9ANPC1NPSR1 | |
| SCHEMBL8615334 | 0.71 | EPHX1 (0.68) | TDP1CTDSP1EPHX1ALDH1A1MAPT | |
| SCHEMBL11492866 | 0.71 | RAB9A (0.75) | TDP1EPHX1ALDH1A1MAPTRAB9A | |
| SCHEMBL19128666 | 0.71 | KMT2A (0.49) | TDP1CTDSP1EPHX1ALDH1A1MAPT | |
| SCHEMBL191773 | 0.71 | NPC1 (0.53) | TDP1CTDSP1EPHX1ALDH1A1MAPT | |
| SCHEMBL2340858 | 0.71 | NPC1 (0.68) | TDP1CTDSP1EPHX1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231653-B1 | ANTIBACTERIAL CONDENSED THIAZOLES | BIOTA EUROPE LTD (GB) | 2013-04-03 | — | — | EP | disclosed |