Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.78 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.78 |
| ▸ | PRKCA | P17252 | 5/20 | 0.78 |
| ▸ | PRKCH | P24723 | 5/20 | 0.78 |
| ▸ | PRKCI | P41743 | 5/20 | 0.78 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.78 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.78 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.78 |
| ▸ | PRKCG | P05129 | 4/20 | 0.78 |
| ▸ | PRKCB | P05771 | 4/20 | 0.78 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.78 |
| ▸ | NTRK1 | P04629 | 9/20 | 0.76 |
| ▸ | KDR | P35968 | 7/20 | 0.76 |
| ▸ | FLT3 | P36888 | 5/20 | 0.76 |
| ▸ | MAP3K11 | Q16584 | 5/20 | 0.76 |
| ▸ | MYLK | Q15746 | 4/20 | 0.76 |
| ▸ | MAP3K9 | P80192 | 4/20 | 0.76 |
| ▸ | MAP3K10 | Q02779 | 4/20 | 0.76 |
| ▸ | CDK4 | P11802 | 3/20 | 0.76 |
| ▸ | CDK2 | P24941 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865254 | 0.91 | NTRK1 (0.74) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL20865255 | 0.91 | PRKCQ (0.73) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL21132411 | 0.90 | NTRK1 (0.85) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL21132751 | 0.90 | NTRK1 (0.85) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL20865122 | 0.89 | PRKCQ (0.71) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL20865256 | 0.89 | PRKCQ (0.71) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL20865257 | 0.89 | PRKCQ (0.70) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL20865110 | 0.88 | NTRK1 (0.70) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL13168059 | 0.88 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI | |
| SCHEMBL3747539 | 0.88 | PRKCQ (1.00) | PRKCQPRKD3PRKCAPRKCHPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8771682-B2 | Methods and compositions for reducing interleukin-4 or interleukin-13 signaling | Technische Universtität Dresden (DE) | 2014-07-08 | — | — | US | disclosed |
| US-8771682-B2 | Methods and compositions for reducing interleukin-4 or interleukin-13 signaling | Technische Universtität Dresden (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20130084275-A1 | Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2013-04-04 | — | — | US | disclosed |
| US-20130084275-A1 | Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130084275-A1 | Methods and Compositions for Reducing Interleukin-4 or Interleukin-13 Signaling | IL4, IL2RA, STAT6 | PRKCQ 174/4885PRKD3 487/4885PRKCA 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.