Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | INSR | P06213 | 13/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12012062 | 0.83 | MAPT (0.52) | CYP2D6TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL14095647 | 0.77 | CYP2D6 (0.81) | CYP2D6TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL30924847 | 0.76 | CYP2D6 (0.79) | CYP2D6TSHRHSD17B10MAPTALDH1A1 | |
| SCHEMBL13084572 | 0.76 | CYP2D6 (0.79) | CYP2D6TSHRHSD17B10MAPTALDH1A1 | |
| Bromide SCHEMBL887660 | 0.76 | CYP2D6 (0.79) | CYP2D6TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL13933959 | 0.75 | MEN1 (0.60) | CYP2D6MAPTMEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL1655741 | 0.74 | CYP2D6 (0.77) | CYP2D6TSHRHSD17B10MAPTALDH1A1 | |
| SCHEMBL26023141 | 0.72 | MAPT (0.60) | CYP2D6TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL10023147 | 0.72 | MAPT (0.60) | CYP2D6TSHRHSD17B10MAPTMEN1 | |
| SCHEMBL30924854 | 0.72 | INSR (0.57) | CYP2D6TSHRHSD17B10MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130084561-A1 | BIODETECTION BY NUCLEIC ACID-TEMPLATED CHEMISTRY | COULL JAMES M (US) | 2013-04-04 | — | — | US | disclosed |