Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 8/20 | 0.60 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.60 |
| ▸ | PDE4A | P27815 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516708 | 0.92 | PDE1A (0.72) | PDE1APDE1BPDE4A | |
| SCHEMBL19447761 | 0.85 | PDE1A (0.66) | PDE1APDE1BPDE4A | |
| SCHEMBL19447765 | 0.83 | PDE1A (0.64) | PDE1APDE1BPDE4A | |
| SCHEMBL15869797 | 0.83 | PDE1A (0.84) | PDE1APDE1BPDE4A | |
| SCHEMBL14827543 | 0.80 | PDE4A (0.85) | PDE1APDE1BPDE4A | |
| SCHEMBL26233377 | 0.79 | PDE1A (0.71) | PDE1APDE1BPDE4A | |
| SCHEMBL17508439 | 0.79 | PDE1A (0.64) | PDE1APDE1BPDE4A | |
| SCHEMBL17508441 | 0.79 | PDE1A (0.79) | PDE1APDE1BPDE4A | |
| SCHEMBL14158337 | 0.78 | PDE1A (0.80) | PDE1APDE1BPDE4A | |
| SCHEMBL17508443 | 0.76 | PDE1A (0.79) | PDE1APDE1BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556185-B2 | Organic compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-01-31 | — | — | US | disclosed |
| US-20130085123-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2013-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085123-A1 | ORGANIC COMPOUNDS | TPMT, TYMS, P2RX4 | PDE1A 4773/4885PDE1B 4779/4885PDE4A 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.