SCHEMBL14827640

SCHEMBL14827640

C[Si](C)(C)COCCOCCOCCO

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
TSHR P16473 2/20 0.53
MAPK1 P28482 2/20 0.53
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.32
APP P05067 4/20 0.30
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CASP1 P29466 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
SLCO1B3 Q9NPD5 1/20 0.30
SLCO1B1 Q9Y6L6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1653327 0.95
SCHEMBL6057337 0.83
Ethylene Glycol SCHEMBL6057331 0.77 TSHR (0.33) MEN1KMT2ATSHRMAPK1ALDH1A1
Hexaethylene Glycol SCHEMBL28265392 0.76 MEN1 (0.85) MEN1KMT2ATSHRMAPK1THRB
Triethylene Glycol SCHEMBL27836955 0.76 MEN1 (0.85) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL4092706 0.76 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL19305255 0.76 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL19000749 0.76 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL5145873 0.76 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB
Tetraethylene Glycol SCHEMBL3343601 0.76 MEN1 (1.00) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9085591-B2 Organosilicon amine electrolyte materials containing polyether chain and application thereof in electrolytes of lithium-ion batteries GUANGZHOU INSTITUTE OF ENERGY CONVERSION, CHINESE ACADEMY OF SCIENCES (CN) 2015-07-21 US disclosed
US-20130084490-A1 ORGANOSILICON AMINE ELECTROLYTE MATERIALS CONTAINING POLYETHER CHAIN AND APPLICATION THEREOF IN ELECTROLYTES OF LITHIUM-ION BATTERIES GUANGZHOU INSTITUTE OF ENERGY CONVERSION,CHINESE ACADEMY OF SCIENCES (CN) 2013-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130084490-A1 ORGANOSILICON AMINE ELECTROLYTE MATERIALS CONTAINING POLYETHER CHAIN AND APPLICATION THEREOF IN ELECTROLYTES OF LITHIUM-ION BATTERIES OR10J3, PRMT7, PRMT6 MEN1 180/4885KMT2A 774/4885TSHR 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.