SCHEMBL148285

SCHEMBL148285

CCOc1cc(C)c(N)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.53
ALDH1A1 P00352 5/20 0.53
HSD17B10 Q99714 4/20 0.53
POLB P06746 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
KDM4E B2RXH2 3/20 0.53
MAPK1 P28482 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
HPGD P15428 1/20 0.53
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
USP2 O75604 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
ALOX15 P16050 2/20 0.45
CYP1A2 P05177 1/20 0.45
CASP7 P55210 1/20 0.45
HIF1A Q16665 1/20 0.45
CREBBP Q92793 1/20 0.44
GAA P10253 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29358090 1.00 MAPT (0.53) MAPTALDH1A1HSD17B10POLBMEN1
Hydrochloric Acid SCHEMBL29358790 0.98 MAPT (0.52) MAPTALDH1A1HSD17B10POLBMEN1
Hydrochloric Acid SCHEMBL10362702 0.98 MAPT (0.52) MAPTALDH1A1HSD17B10POLBMEN1
Hydrochloric Acid SCHEMBL3341943 0.98 MAPT (0.52) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL4245018 0.92 GAA (0.51) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL11653686 0.91 ALDH1A1 (0.53) MAPTALDH1A1HSD17B10POLBMEN1
Sulfuric Acid SCHEMBL2480079 0.89 HSD17B10 (0.46) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL653555 0.87 ALDH1A1 (0.48) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL7028420 0.84 MAPT (0.64) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL21616261 0.83 ALDH1A1 (0.48) MAPTALDH1A1HSD17B10POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1873 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
CN-108670871-A A kind of hair dye and its application method 花安堂生物科技集团有限公司 2018-10-19 CN claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP claimed
EP-1674075-B1 Hair colouring process comprising a cleaning step ORÉAL L (FR) 2016-07-20 EP claimed
WO-2015112789-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO claimed
EP-1778176-B1 COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES HENKEL AG & CO KGAA (DE) 2012-07-25 EP claimed
US-8043385-B2 Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof L'OREAL S.A. (FR) 2011-10-25 US claimed
WO-1991018583-A1 OXIDATIVE HAIR DYE CONTAINING 3-AMINOPHENOL DERIVATIVES, PROCESS FOR OXIDATIVE DYEING OF HAIR AND NEW 3-AMINOPHENOL DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1991-12-12 WO claimed
US-5061289-A AS DEVELOPERS WELLA AKTIENGESELLSCHAFT (DE) 1991-10-29 US claimed
WO-1991009587-A1 AGENT AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR WELLA AKTIENGESELLSCHAFT (DE) 1991-07-11 WO claimed
US-4997451-A Developers WELLA AKTIENGESELLSCHAFT (DE) 1991-03-05 US claimed
EP-0395837-A1 Oxidation hair dyes based on 4-aminophenol derivatives as well as new 4-aminophenol derivatives Wella Aktiengesellschaft (DE) 1990-11-07 EP claimed
EP-0252351-B1 5-ALKOXY-2,4-DIAMINO-ALKYLBENZENES AND HAIR DYES CONTAINING SAME Wella Aktiengesellschaft (DE) 1990-09-12 EP claimed
WO-1990007504-A1 OXIDATION HAIR-DYEING AGENT CONTAINING DIAMINOPYRAZOLE DERIVATIVES AND NOVEL DIAMINOPYRAZOLE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 1990-07-12 WO claimed
EP-0375977-A1 Oxidation hairdyeing composition based upon diaminopyrazole derivatives, and these diaminopyrazole derivatives Wella Aktiengesellschaft (DE) 1990-07-04 EP claimed
US-4854935-A OXIDATION COLOR DYE COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1989-08-08 US claimed
EP-0252351-A1 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same Wella Aktiengesellschaft (DE) 1988-01-13 EP claimed