Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | NMT2 | O60551 | 1/20 | 0.30 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14828957 | 0.86 | HRH4 (0.34) | HRH4JAK3NMT2NMT1 | |
| SCHEMBL14829160 | 0.85 | PDE10A (0.38) | HRH4JAK3 | |
| SCHEMBL14829030 | 0.84 | HRH4 (0.35) | HRH4 | |
| SCHEMBL14828974 | 0.80 | HRH4 (0.43) | HRH4 | |
| SCHEMBL14828924 | 0.79 | HRH4 (0.36) | HRH4 | |
| SCHEMBL14828930 | 0.78 | HRH4 (0.36) | HRH4 | |
| SCHEMBL14828879 | 0.77 | OPRM1 (0.32) | HRH4 | |
| SCHEMBL14828804 | 0.76 | POLB (0.41) | HRH4 | |
| SCHEMBL14829152 | 0.76 | HRH4 (0.66) | HRH4 | |
| SCHEMBL14828981 | 0.75 | HRH4 (0.39) | HRH4JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760865-A2 | NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES | C&C Research Laboratories (KR) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013048214-A2 | NOVEL HETEROCYCLIC DERIVATIVES AND THEIR USES | C&C RESEARCH LABORATORIES (KR) | 2013-04-04 | — | — | WO | disclosed |