Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.56 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829004 | 0.87 | MAPT (0.71) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13912 | 0.83 | KMT2A (0.75) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL975489 | 0.83 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL6689700 | 0.81 | GFER (1.00) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL429085 | 0.80 | MAPT (0.75) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL9382745 | 0.80 | MAPT (0.75) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL3369741 | 0.80 | ALDH1A1 (0.55) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL12845036 | 0.80 | ALDH1A1 (0.57) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL13007050 | 0.79 | ALDH1A1 (0.53) | MAPTKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7302053 | 0.79 | MAPT (0.73) | MAPTKMT2AMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760823-A1 | NOVEL COMPOUNDS AS HIF-1ALPHA INHIBITORS AND MANUFACTURING PROCESS THEREOF | Dongguk University Industry-Academic Cooperation Foundation (KR) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013048164-A1 | NOVEL COMPOUNDS AS HIF-1αINHIBITORS AND MANUFACTURING PROCESS THEREOF | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2013-04-04 | — | — | WO | disclosed |